TY - T1的无创性通气支持不促进复苏在慢性阻塞性肺疾病急性呼吸衰竭JF -欧洲呼吸杂志》乔和J SP - 1240 LP - 1245欧元六世- 9 - 6盟Barbe F AU - Togores, B非盟- Rubi M AU -脑桥,年代盟——Maimo盟——Agusti AG Y1 - 1996/06/01 UR - //www.qdcxjkg.com/content/9/6/1240.abstract N2 -这个调查评估,前瞻性,随机和控制方式,是否无创通气支持(纳伟仕),上下两层的正压通气(BiPAP)促进康复急性呼吸衰竭(ARF)在慢性阻塞性肺疾病(COPD)患者。二十4名患者(平均年龄(+钙)68 + / - 2岁)与慢性阻塞性肺病(一秒用力呼气量(FEV1)排放预测33 + / - 2%),参加了急诊室,因为ARF (pH值7.33 + / - 0.01;动脉氧张力(Pa, O2) 6.0 + / - 0.2 kPa;动脉二氧化碳张力(Pa、二氧化碳)7.9 + / - 0.3 kPa),最初是随机的。四的14个病人(29%)分配给了纳伟仕不容忍它。剩下的20名患者,10收到纳伟仕BiPAP在传统的医院病房住院的前3天(两个白天会话3 h时间)。所有20个受试者接受氧气,支气管扩张药和类固醇。在第一和第三个住院几天,之前和30分钟后取出氧疗法和/或BiPAP通气支持,我们测量呼气流量峰值,动脉血气值,通气模式,阻塞压力(P0.1)和最大吸气(MIP)和最大呼气(MEP)的压力。所有患者出院不需要气管插管,机械通气。两组住院时间是相似的(11.3 + / - 1.3 vs 10.6 + / - 0.9天,控制vs BiPAP,分别)。 Arterial oxygenation, respiratory acidosis and airflow obstruction improved significantly throughout hospitalization in both groups. By contrast, the ventilatory pattern, P0.1, MIP and MEP did not change. NIVS with BiPAP did not cause any significant difference between groups. We conclude that noninvasive ventilatory support with bilevel positive airway pressure does not facilitate recovery from acute respiratory failure in patients with chronic obstructive pulmonary disease. Furthermore, a substantial proportion of patients (29%) do not tolerate noninvasive ventilatory support under these circumstances. From these results, we cannot recommend the use of noninvasive ventilatory support with bilevel positive airway pressure in the routine management of chronic obstructive pulmonary disease patients recovering from acute respiratory failure. ER -