TY - T1的遵守指导方针预防艾滋病毒相关的呼吸道疾病JF -欧洲呼吸杂志》乔欧元和J SP - 2318 LP - 2322 - 10.1183 / 09031936.96.09112318六世- 9 - 11盟JS褐煤AU - P菲利普斯AU - C硼砂盟KJ Craib AU - MV O ' shaughnessy盟太Schechter Y1 - 1996/11/01 UR - //www.qdcxjkg.com/content/9/11/2318.abstract N2 -在这项研究中,我们使用的模式特征的预防性治疗特定的呼吸并评估了针对性反馈对这些疾病指南依从性水平的影响。在我们的队列中，所有人类免疫缺陷病毒血清阴性(HIV-) (n=169)和获得性免疫缺陷综合征(AIDS)无人类免疫缺陷病毒血清阳性(HIV+) (n=154)的参与者，都在1989年10月至1993年12月期间完成了4次年度随访。每位受试者每年获得纯化蛋白衍生物(PPD)(结核菌素)检测、肺炎球菌疫苗接种史、流感疫苗接种、卡氏肺孢子虫肺炎(PCP)预防使用、症状和CD4计数等信息。1992年，向参与的医生提供了关于遵守当代预防呼吸道疾病准则的总体水平的反馈。作为这项工作的一部分，分发和讨论了指导方针。在研究期间，接受PPD检测的HIV阳性患者比例从43%增加到65% (p=0.001)。接受PPD检测的HIV+患者明显多于HIV-患者(p<0.001)。共有144名(94%)HIV阳性男性接受了至少一次流感疫苗接种，而60名(35%)HIV阳性男性(p<0.001)。艾滋病毒阳性组的流感疫苗接种率从1992年的78%显著增加到1993年的92% (p<0.001)。 A total of 104 (68%) HIV+ men received pneumococcal vaccination compared to 2 (1%) HIV- men (p<0.001). Among HIV+ individuals whose absolute CD4+ count was less than 200 cells x mm(-3), the percentage of men who received primary PCP prophylaxis was 0, 86, 72 and 88 for the years 1990-1993, respectively. Among HIV+ patients whose only eligibility criterion for PCP prophylaxis was a CD4+ percentage <20%, compliance was 55, 30, 37 and 50% for the years 1990-1993, respectively. Among HIV+ subjects, increases in the compliance level were noted for all preventive therapies after targeted feedback was provided during the last quarter of 1992. However, only utilization of influenza vaccine exceeded a 90% compliance in 1993. These data demonstrate that a suboptimal level of compliance with current guidelines for the prevention of respiratory disease among human immunodeficiency virus-infected individuals can be significantly improved using targeted feedback. Although it is likely that similar effects could be achieved in other populations or the community at large, this remains to be demonstrated. ER -