TY - T1的家庭康复对物理性能的影响慢性阻塞性肺疾病(COPD)患者JF -欧洲呼吸杂志》乔和J SP - 104 LP - 110欧元六世- 9 - 1 AU Wijkstra PJ AU - van der马克,TW盟——Kraan J AU - van Altena R盟——Koeter GH AU - Postma,DS Y1 - 1996/01/01 UR - //www.qdcxjkg.com/content/9/1/104.abstract N2 -我们调查是否在家12周的康复对慢性阻塞性肺病(COPD)患者有益的影响乳酸生产,代谢气体交换数据,工作量的吸气肌肉,在最大自行车力量器测试中出现呼吸困难。第二个目的是评估呼吸困难的变化是否与吸气肌负荷的变化有关。43例严重气道阻塞的COPD患者被纳入研究:平均1秒用力呼气量(FEV1) 1.3 +/- 0.4 L(44%预测)，平均FEV1/吸气肺活量(IVC) 37 +/- 8%。28名病人开始接受康复治疗，15名病人没有接受康复治疗。康复在家中进行;病人由一名全科医生、一名物理治疗师和一名护士监督。通过6分钟步行距离测试(6MWD)和最大工作量(Wmax)测量运动耐量，同时进行递增症状受限循环功计测试。用张力时间指数(TTI)评估Wmax时吸气肌负荷，用Borg量表评估Wmax时呼吸困难。 After 12 weeks, the rehabilitation group showed a significantly larger increase in 6MWD (from 438 to 447 m) and in Wmax (from 70 to 78 W) compared with the control group. A significant improvement in oxygen consumption (V1O2) (from 1.0 to 1.1 L), lactate level (from 3.7 to 3.1 mEq.L(-1)), dyspnoea (from 6.0 to 4.5) and TTI (from 0.10 to 0.08) at Wmax occurred in the rehabilitation group during the programme. The reduction in TTI was not significantly correlated with the fall in dyspnoea, as assessed by the Borg scale. We conclude that 12 weeks of rehabilitation at home in COPD patients increases symptom-limited V1O2 in combination with an increased Wmax. At this significantly higher Wmax, there was a reduction in dyspnoea, lactate level and inspiratory muscle workload. The reduction in dyspnoea was not related to a decreased inspiratory muscle workload. This study shows that rehabilitation at home can produce beneficial physiological improvements during exercise in patients with chronic obstructive pulmonary disease. ER -