PT -期刊文章AU - Soguel Schenkel, N AU - Burdet, L AU - de Muralt, B AU - Fitting，JW TI -氧饱和度在日常活动在慢性阻塞性肺病DP - 1996年12月01 TA -欧洲呼吸杂志》第六PG - 2584 - 2589 - 9 IP - 4099年12 - 4100年//www.qdcxjkg.com/content/9/12/2584.short //www.qdcxjkg.com/content/9/12/2584.full所以欧元和J1996 12月01;9 AB -慢性阻塞性肺疾病(COPD)患者常因肺泡通气不足、通气灌注不匹配加重、有时伴有阻塞性睡眠呼吸暂停而发生夜间氧破坏。相比之下，人们对它们在日常生活中各种活动中的氧状态知之甚少。本研究的目的是比较昼夜氧饱和度，并评估不同日常活动对COPD患者的影响。在一项康复计划中，我们研究了30例中度至重度COPD患者(1秒中位用力呼气量(FEV1)为预测的37%)，无明显低氧血症(中位动脉氧张力(Pa,O2) 9.1 kPa)。采用脉搏血氧仪测定夜间(8 h)和白天(10.5 h)的动脉血氧饱和度(Sa、O2)，计算Sa、O2的平均值和最小值，去饱和度定义为Sa、O2下降>.h-1 4%。患者的日常活动包括休息、进食、清洗、雾化治疗和行走。平均Sa,O2在夜间(88%)低于白天(89%)。 In contrast, minimal Sa,O2 was lower during the day (69%) than during the night (72%), and the number of desaturations was higher during the day (8.6 desaturations.h-1) than during the night (6.8 desaturations.h-1). Mean Sa,O2 was 88% during walking, which was lower than during resting (90%), nebulization (90%), and meals (89%). The number of desaturations was higher during walking (13.1 desaturations.h-1), washing (12.6 desaturations.h-1), and eating (9.2 desaturations.h-1) than during resting (5.3 desaturations.h-1). We conclude that daily activities, such as walking, washing and eating, are associated with transient oxygen desaturation in patients with moderate-to-severe chronic obstructive pulmonary disease, even without marked resting hypoxaemia.