TY - T1的肺容积的影响在transdiaphragmatic压力JF -欧洲呼吸杂志》乔和J SP - 1532 LP - 1536欧元六世- 8 - 9盟Hamnegard CH盟——Wragg年代非盟-米尔斯,G盟——Kyroussis D AU -路,J盟——Daskos G盟——烤,B非盟- Moxham J盟——绿色,N2 -可以通过测量膈神经刺激后的经膈压(Pdi)来评估膈肌强度。通过测量肺容积范围内的抽搐Pdi，可以研究横膈膜的长度-张力关系。以往关于肺容量与膈肌强度关系的研究都使用了电刺激膈神经的技术。在这些研究中，没有考虑到抽搐增强的现象。以前已经证明，事先收缩横膈膜可以大大增强抽搐反应，从而影响测量。本研究的目的是探讨正常受试者无电位性抽搐Pdi与肺容量(从残气量(RV)到总肺容量(TLC))之间的关系。小心避免肌肉增强。为此，我们用磁刺激器刺激膈神经。此外，我们使用正压充气肺到高肺容量。 The impact of twitch potentiation on the length-tension relationship was investigated by subjects making maximum inspiratory efforts prior to phrenic nerve stimulation. The unpotentiated twitch Pdi decreased in a linear fashion with increasing lung volume over the full range of vital capacity by 0.54 kPa.L-1. Potentiation increased twitch Pdi by 40% at FRC and the effect was similar, in absolute terms, at all lung volumes. In relative terms, the effect of potentiation became greater as lung volume increased, and more than doubled twitch Pdi at TLC. With increasing lung volume, there is a linear fall in unpotentiated twitch Pdi with a slope that is less steep, over the same range of absolute lung volume, than previously reported. When assessing diaphragm strength by the twitch technique, it is essential to control for lung volume and equally important to control for twitch potentiation. ER -