TY - JOUR T1 - Priming of circulating human eosinophils following late response to allergen challenge JF - European Respiratory Journal JO - Eur Respir J SP - 703 LP - 708 DO - 10.1183/09031936.96.09040703 VL - 9 IS - 4 AU - Evans, DJ AU - Lindsay, MA AU - O'Connor, BJ AU - Barnes, PJ Y1 - 1996/04/01 UR - //www.qdcxjkg.com/content/9/4/703.abstract N2 - The eosinophil is recognized as an important effector cell in asthma.研究生态哮喘的作用 研究外围血液生态素研究19个温室哮喘科,每人显示迟发哮喘响应exigen挑战后e2O2释放测量:1)小板激活因子并补充因子5a和2前单元生存实验题前和24小时后都曾破解过敏挑战,而生态素则由免疫磁分解编译Basal H2O2释放量增加 从eosnophics响应PAF刺激在细胞敏感度(负集中日志产生最大效果的一半(pD2))和响应性(最大效果Emax)方面大增C5a敏感度不变,但最大响应量大增ex-vivoeosnophil生存(3天和细胞半衰期)在过敏挑战后大大延长归根结底,我们已经证明循环eosnophicsER-