@文章{Guillemi33，作者= {Guillemi, SA和Staples, CA和Hogg, JC和Le, AN和Lawson, LM和Schechter, MT和Montaner, JS}，标题={晚期HIV疾病患者高分辨率计算机断层扫描(HRTC)中意外的肺部病变}，卷={9}，数={1}，页数={33—36}，年份= {1996}，doi ={10.1183/09031936.96.09010033}，出版商={欧洲呼吸学会}，188bet官网地址目前的试点研究是为了描述无症状的人类缺陷病毒(HIV)感染晚期HIV患者肺部病变的频率。对32名连续的HIV阳性同性恋男性进行前瞻性研究，评估他们是否开始对卡氏肺孢子虫肺炎(PCP)进行预防。所有患者均进行了完整的病史、体格检查、肺功能检查和高分辨率计算机断层扫描(HRCT)。HRCT扫描由一名放射科医生读取，他对患者的临床状况一无所知。60%的患者在HRCT扫描中发现意外病变。HRCT正常与异常患者在年龄、身高、体重、CD4+计数、吸烟史、血清白蛋白、α - 1-抗胰蛋白酶水平、体重指数等方面差异无统计学意义。用力肺活量(FVC) (\% of expected)和峰值呼气流量(PEFR) (\% pred)两组间差异无统计学意义。HRCT正常和异常患者1秒用力呼气量(FEV1) (\% pred)分别为99 +/- 12 vs 92 +/- 16, FEV1/FVC为82 +/- 5 vs 76 +/- 9，用力呼气中流量(FEF25-75) (\% pred)分别为100 +/- 24 vs 77 +/- 27。出现破坏性和非破坏性肺部HRCT病变的患者之间没有统计学上的显著差异。 Our results demonstrate that as many as 60\% of HIV-infected patients have unexpected abnormalities on HRCT at the time of starting PCP prophylaxis. We speculate that these lesions may contribute to the high frequency of spontaneous pneumothoraces previously reported in this patient population.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/9/1/33}, eprint = {//www.qdcxjkg.com/content/9/1/33.full.pdf}, journal = {European Respiratory Journal} }