ty -jour t1-呼气PCO2与体积曲线的2阶段是否在肺气肿患者中具有诊断值?JF-欧洲呼吸杂志JO -EUR RESSIR J SP -86 LP -92 VL -8 IS -1 AU -KARS,AH AU -GOORDEN,GAU -GAU -Stijnen,T au -Bogaard,JM Au -jm au -verbraak -verbraak,af au -hilvering -hilvering -hilvering,C Y1-1995/01/01 UR -http://www.qdcxjkg.com/content/8/1/86.abstract N2-假定emphysema中外围气道中通风的串行不均匀性由emphysema代表呼气二氧化碳张力与体积曲线的形状。我们检查了该测试的诊断价值在不同程度的肺气肿患者中。在29名强度的患者中,确定了25-50%(V25-50)(V25-50)和25-75%(V25-75)(V25-75)的体积(V25-75)与体积曲线确定(20例严重阻塞和9名中度受阻),12名哮喘患者在加剧症状和28个健康对照方面。使用判别分析来检查这些诊断组是否可以分离。关于呼气二氧化碳与体积曲线的2阶段(解剖空间和肺泡空气的混合物),(v25-50)和(v25-75)和(v25-75)的截距与启动量(VI)的关系图(VI)在自然呼吸频率期间获得的功能残留能力(FRC)在健康对照组和严重阻塞肺气肿患者之间的分离中被证明是最歧视的。 Separating healthy controls and severely obstructed emphysema patients on the basis of the discriminant line for V25-50, 9 of the 12 asthma patients in exacerbation were classified as normal, and only 5 of the 9 moderately obstructed emphysema patients as emphysematous. For V25-75 involvement of phase 3 of the curve (alveolar plateau) in asthma patients in exacerbation caused a marked overlap with the severely obstructed emphysema patients. In the healthy controls, a fixed breathing frequency of 20 breaths.min-1 led to an increase of both volumes.(ABSTRACT TRUNCATED AT 250 WORDS) ER -