%0期刊文章%a siafakas,nm%a argyrakopoulos,t%a andreopoulos,k%a tsoukalas,g%a tzanakis,n%a bouros,d%t呼吸肌肉在连续室内腹膜​​透析期间(CAPD)d 1995 d 1995 d 1995 d 1995%j欧洲呼吸杂志%p 109-113%v 8%n 1%x这项研究的目的是研究慢性肾衰竭(CRF)和连续的卧床腹膜透析(CAPD)对呼吸肌功能的影响。在26名患者中,通过测量最大静态灵感(PIMAX)在残留体积(RV)和到期(PEMAX)的最大静态灵感(PIMAX)期间的口腔压力(PIMAX)在总肺部容量(TLC)附近评估全球呼吸肌强度。在透析前,在透析前4小时,在腹膜腔中和下一次排水后,测量了最大压力,肺活量测定法和肺部体积。此外,在治疗前测量了一次生化指数(尿素,肌酐,钠,钾,钙和磷)和血液学指数(血红蛋白(HB)和血细胞比容(HCT))。结果表明,在CAPD之前,平均PIMAX和PEMAX正常,患者之间的范围很大。然而,七名患者(27%)的PIMAX <75%预测(PREP)和八名(31%)pemax <75%pred。在CAPD期间,最大压力显着下降,并在流体引流后再次增加。同样,肺部体积在正常范围内,在CAPD期间显着下降。强迫呼气量在一秒钟内,强迫生命力(FEV1/FVC)比率没有改变。 We conclude that respiratory muscle strength was preserved in the majority of the patients with chronic renal failure treated with CAPD. During CAPD, lung volumes and respiratory muscle function were decreased, demonstrating an effect of the abdominal cavity on the mechanics of the respiratory system. However, the decrease in the maximum pressures was less than 20%, indicating that CAPD is a safe procedure in patients without pre-existing pulmonary disease or uraemic pulmonary complications.(ABSTRACT TRUNCATED AT 250 WORDS) %U //www.qdcxjkg.com/content/erj/8/1/109.full.pdf