TY - JOUR T1 - A的表达在哮喘和慢性阻塞性肺病的支气管扩张反应的六种不同方法的比较;再现性和支气管扩张FEV1 JF的依赖性 - 欧洲呼吸杂志JO - EUR呼吸杂志SP - 975 LP - 981 VL - 5 IS - 8 AU - Dompeling，E AU - 面包车Schayck，CP AU - Molema，J AU - Akkermans，R AU- Folgering，H AU - 面包车Grunsven，PM AU - 面包车的Weel，Y1ç - 1992年9月1日UR - //www.qdcxjkg.com/content/5/8/975.abstract N2 - 各种索引用于表达支气管扩张反应。目前还不清楚，但是，这指数最翔实。本研究的目的是比较在支气管扩张反应六个表达式和检查：1）用力呼气容积一秒（FEV1）的支气管扩张的独立性;和2）支气管扩张反应的再现性。支气管扩张响应从一个大的支气管扩张干预研究（增加FEV1 60分钟沙丁胺醇400微克和异丙托溴铵80微克后）在六个试验的场合，在两年中，183例（72哮喘，111慢性阻塞性肺病（COPD））为用过的。所述支气管扩张FEV1的依赖性患者（截面分析）之间，并通过线性回归分析的装置例（纵向分析）内研究两者。 The reproducibility of the bronchodilating response was calculated by means of the coefficients of variation (CVs) of the six bronchodilating responses during two years. The CVs of the six expression indices were compared by analysis of variance (ANOVA). No index was independent of the prebronchodilator FEV1. However, some indices were significantly more dependent on the prebronchodilator lung function and, therefore, less reproducible than others. The "% initial" index (change as a percentage of the prebronchodilator value) was the most dependent on the prebronchodilator lung function and had the worst reproducibility (CV ranged from 50-61%). The "% possible" (change as a percentage of the predicted minus prebronchodilator value) and "% achievable" (change as a percentage of the maximal postbronchodilator minus prebronchodilator value) indices were the least dependent on the prebronchodilator value and had the highest reproducibility (CV ranging from 34-53%).(ABSTRACT TRUNCATED AT 250 WORDS) ER -