TY -的T1 -作者:摩根富林明——欧洲Respiratory Journal JO - Eur Respir J SP - 1223 LP - 1223 DO - 10.1183/09031936.00127310 VL - 36 IS - 5 AU - Aliverti, A. AU - Lo Mauro, A. AU - D'Angelo, M.G. Y1 - 2010/11/01 UR - //www.qdcxjkg.com/content/36/5/1223.abstract N2 - From the authors:We thank P. Wijkstra and co-workers for their interest and comments regarding our paper, “Abdominal volume contribution to tidal volume as an early indicator of respiratory impairment in Duchenne muscular dystrophy” 1. They wonder if our findings of progressive drop of abdominal contribution to tidal volume in Duchenne muscular dystrophy (DMD) are somewhat related to: 1) differences in forced vital capacity (FVC) between sitting and supine position; and 2) nocturnal hypercapnia. These questions are of great interest and they deal with three key aspects regarding the prognosis and the management of patients with DMD and other primary neuromuscular diseases, namely the noninvasive assessment of diaphragm function, the evaluation of sleep disordered breathing and the choice of the correct timing for the introduction of nocturnal noninvasive mechanical ventilation.Unfortunately, we are not able … ER -