TY - T1的耐甲氧西林金黄色葡萄球菌引起的肺部感染我ncluding airway infection, community-acquired pneumonia and hospital-acquired pneumonia JF - European Respiratory Journal JO - Eur Respir J SP - 1470 LP - 1476 DO - 10.1183/09031936.00122309 VL - 34 IS - 6 AU - Defres, S. AU - Marwick, C. AU - Nathwani, D. Y1 - 2009/12/01 UR - //www.qdcxjkg.com/content/34/6/1470.abstract N2 - Staphylococcus aureus has been recognised as a cause of community-acquired pneumonia, albeit uncommon, and an important cause of healthcare-associated (HA) pneumonia, including ventilator-associated pneumonia. Resistance of S. aureus to methicillin developed shortly after its introduction into clinical practice. Since then, methicillin-resistant S. aureus (MRSA) has predominantly been a feature of hospital-acquired, or latterly HA, infections as the boundaries became more blurred between the community and hospital environments. However, more recently true community-acquired (CA)-MRSA infections have been detected and are becoming increasingly common, especially in the USA. Europe has not been immune to the development of MRSA in healthcare settings and although the prevalence of CA-MRSA is currently relatively low, there is the risk of wider spread. These new CA-MRSA strains appear to behave differently to HA-MRSA strains. Although predominantly causing skin and soft tissue infections, mainly as boils and abscesses requiring drainage, life threatening invasive infections including necrotising pneumonia can also occur. This article summarises the pathogenesis and clinical presentations of MRSA-related lung infections. SERIES “MRSA AND THE PULMONOLOGIST” Edited by M. Woodhead and A. Torres Number 2 in this Series ER -