TY - T1的分枝杆菌的致病性tuberculosis during chemotherapy JF - European Respiratory Journal JO - Eur Respir J SP - 399 LP - 402 VL - 3 IS - 4 AU - Clancy, LJ AU - Kelly, P AU - O'Reilly, L AU - Byrne, C AU - Costello, E Y1 - 1990/04/01 UR - //www.qdcxjkg.com/content/3/4/399.abstract N2 - We used the guinea pig as an experimental model to investigate the pathogenicity of Mycobacterium tuberculosis. Sputum samples were injected subcutaneously into guinea pigs and the animals were killed and an autopsy performed after eight weeks. The likelihood of the sputum samples producing tuberculosis in the guinea pig was related to culture positivity rather than to duration of chemotherapy. This study does not support the belief that a change in pathogenicity occurs during treatment of pulmonary tuberculosis. ER -