作者@article {Rabiller108 = {Rabiller, a和Ja{\"\i}s, X. and Hamid, A. and Resten, A. and Parent, F. and Haque, R. and Capron, F. and Sitbon, O. and Simonneau, G. and Humbert, M.}, title = {Occult alveolar haemorrhage in pulmonary veno-occlusive disease}, volume = {27}, number = {1}, pages = {108--113}, year = {2006}, doi = {10.1183/09031936.06.00054105}, publisher = {European Respiratory Society}, abstract = {Pulmonary veno-occlusive disease (PVOD) is a rare cause of pulmonary arterial hypertension that affects predominantly post-capillary pulmonary vessels. A major concern with PVOD is the poor response to available therapies and the risk of pulmonary oedema with continuous intravenous epoprostenol. The present authors hypothesised that alveolar haemorrhage may be a characteristic feature of pulmonary veno-occlusive disease, as compared with other forms of pulmonary arterial hypertension that predominantly involve pre-capillary pulmonary arteries. This paper reports a series of 19 patients with either PVOD (n = 8) or idiopathic pulmonary arterial hypertension (IPAH; n = 11) who underwent bronchoalveolar lavage. Cytological analyses were performed and differential counts were made on Perls-stained preparations. The Golde score was used to assess alveolar haemorrhage. As compared with IPAH, PVOD was characterised by a higher percentage of haemosiderin-laden macrophages (40{\textpm}37 versus 3{\textpm}6\%), resulting in elevated Golde scores (81{\textpm}88 versus 4{\textpm}10). It was concluded that occult alveolar haemorrhage is a common feature of pulmonary veno-occlusive disease. Detecting occult alveolar haemorrhage may be of interest in the diagnostic approach of pulmonary veno-occlusive disease.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/27/1/108}, eprint = {//www.qdcxjkg.com/content/27/1/108.full.pdf}, journal = {European Respiratory Journal} }