TY - T1的诊断指南和treatment of adult lower respiratory tract infections: a true “European cooperative effort” JF - European Respiratory Journal JO - Eur Respir J SP - 979 LP - 981 DO - 10.1183/09031936.05.00102105 VL - 26 IS - 6 AU - Restrepo, M. I. AU - Anzueto, A. Y1 - 2005/12/01 UR - //www.qdcxjkg.com/content/26/6/979.abstract N2 - Throughout history, the diagnosis and treatment of lower respiratory tract infections (LRTIs) has been a “European cooperative effort”. Since the experiments of R. Koch, many scientists have identified the role of infectious agents, including bacteria, in these conditions and different alternative treatments required to combat them. In 1888, E. de Freudenreich isolated bacterial secretions and noted their inherent, antibacterial properties. Later, in 1896, E. Duchesne noted that certain penicillium moulds killed bacteria, findings that were later confirmed by A. Fleming. We all know the history that follows …, but today we have new challenges to overcome. In the current issue of the European Respiratory Journal, Woodhead et al. 1 present the guidelines of the European Respiratory Society (ERS) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID), based on a systematical appraisal of the existing literature for diagnosis and management of adult LRTIs. These guidelines provide recommendations for the diagnosis and treatment of the three most common LRTIs: community-acquired pneumonia (CAP), acute exacerbations of chronic obstructive pulmonary disease (COPD; AECB) and exacerbations of bronchiectasis. CAP remains a common, serious and potentially life-threatening disease, particularly in elderly patients and those subjects associated with risk factors for resistant pathogens 2, 3. Multiple sets of CAP guidelines have been published in order to address the continued changes in the complexity of this disease, including those in prior versions of the ERS guidelines 4–9. These guidelines help clinicians to stratify patients by risk factors, and provide a range of diagnostic and treatment options in the community, hospital wards or intensive care units. The implementation of CAP guidelines have resulted in a significant reduction … ER -