TY-JUR T1 - 吸入皮质类固醇和儿童肺功能的生长JF - 欧洲呼吸期刊JO - EUR RESPIR J SP - 795 LP - 796 DO - 10.1183 / 09031936.04.00035304 VL - 23是 - 6 Au - Silverman，M。Y1 - 2004/06/01 UR - //www.qdcxjkg.com/content/23/6/795.abstract n2 - 本月的欧洲呼吸杂志版包含两篇论文，解决了效果的重要课题吸入的皮质类固醇（ICS）在儿童时期的肺部发育，2。论文很重要，因为：1）他们提出了关于儿童结果研究设计的重要方法问题;2）他们说明了不同年龄组中肺功能测量的不同方法（分别学龄前儿童和青少年）;3）他们提出了关于肺部结构和功能之间的关系的问题;and 4) they fuel the debate about the appropriate choice of outcomes in managing ICS therapy in children.这些点反过来又被认为是下面的。首先，两项研究的设计是完全不同的。devulapalli等。1对纵向观察研究进行了对群体样本的纵向观察研究，其中将被规定的幼儿与未经处理的症状和无症状的群体进行比较。 Although the design is justified as being “based upon … real life”, it suffers from the shortfall that an independent effect of ICS on functional outcome cannot be deduced from the results presented. At best, it is possible to conclude that both treated and untreated young children with recurrent bronchial obstruction appear functionally to return towards normal by 2 yrs of age. Multivariate analysis might have added strength to the assumption that this process was indeed related in someway to ICS therapy, rather than being simply … ER -