TY - T1的转录后再保险的作用gulation in chemokine gene expression in inflammation and allergy JF - European Respiratory Journal JO - Eur Respir J SP - 933 LP - 947 DO - 10.1183/09031936.05.00120204 VL - 26 IS - 5 AU - Fan, J. AU - Heller, N. M. AU - Gorospe, M. AU - Atasoy, U. AU - Stellato, C. Y1 - 2005/11/01 UR - //www.qdcxjkg.com/content/26/5/933.abstract N2 - The aim of this review is to discuss recent advances in the understanding of the regulation of chemokine expression occurring during chronic inflammatory conditions, such as allergic diseases. The focus will be on current data, which suggest that post-transcriptional regulation plays a larger role in chemokine gene regulation than previously recognised. In particular, a growing body of data indicates that mechanisms controlling mRNA stability may be relevant in determining, or maintaining, the increased levels of chemokine gene expression in this context. Such regulatory pathways may be important targets of novel anti-inflammatory strategies. SERIES “SIGNALLING AND TRANSCRIPTIONAL REGULATION IN INFLAMMATORY AND IMMUNE CELLS: IMPORTANCE IN LUNG BIOLOGY AND DISEASE” Edited by K.F. Chung and I.M. Adcock Number 1 in this Series ER -