TY -的T1 -血红素加氧酶1表达dimi应承担的nished in alveolar macrophages of patients with COPD JF - European Respiratory Journal JO - Eur Respir J SP - 652 LP - 653 DO - 10.1183/09031936.04.00127904 VL - 23 IS - 4 AU - Slebos, D‐J. AU - Kerstjens, H.A.M. AU - Rutgers, S.R. AU - Kauffman, H.F. AU - Choi, A.M.K. AU - Postma, D.S. Y1 - 2004/04/01 UR - //www.qdcxjkg.com/content/23/4/652.abstract N2 - To the Editor: We read with great interest the paper by Maestrelli et al. 1 recently published in the European Respiratory Journal (ERJ). They showed a lower expression of haem oxygenase‐1 (HO‐1) in alveolar macrophages in lung tissue samples of patients with chronic obstructive pulmonary disease (COPD) than of controls. Unfortunately, the authors included a mixed group of smokers and nonsmokers. This makes their results more difficult to interpret since cigarette smoke is known to influence HO‐1 expression as shown in an earlier paper by the same authors 2. Furthermore, the lung tissue samples in their COPD patient group were mainly derived by lung volume resection surgery and in the control group from resection because of lung cancer 1. We … ER -