PT -期刊文章盟M.W.H. Pijnenburg AU - E.T. Lissenberg AU - w . Hofhuis AU - l . Ghiro盟W.C.J.跳AU - W.P.荷兰盟J.C. de Jongste TI -呼出一氧化氮测量与动态流量限制在4 - 8岁的儿童年援助- 10.1183 / 09031936.02.01282002 DP - 2002 10月01 TA -欧洲呼吸杂志》第六PG - 919 - 924 - 20的IP - 4 4099 - //www.qdcxjkg.com/content/20/4/919.short 4100 - //www.qdcxjkg.com/content/20/4/919.full所以欧元和J2002 10月01;20 AB -分数呼出一氧化氮浓度(FEno)取决于呼气流量;然而,孩子们常常无法执行控制流程序。因此,设备开发离线FEno抽样,用动态流动限制(DFR)。作者比较了离线和在线FEno,评估可行性,获得正常的值FEno在4 - 8岁的儿童年。受试者吸入一氧化氮(NO)无空气和呼出到设备,DFR保持呼气流量恒定在50毫升·s−1。死腔空气丢弃。呼出空气中收集150毫升聚酯薄膜气球。进行在线测量和价值观与离线FEno 19个成人志愿者。七十九名儿童进行离线取样。 All samples were analysed with a chemiluminescence NO-analyser. Normal values were obtained in 34 healthy children. There was an excellent correlation between on- and off-line values. Bland and Altman plots showed good agreement between on- and off-line FEno. Seventy-four out of 79 children were able to perform a correct off-line procedure. Geometric mean±sem FEno in healthy children was 4.9±1.2 parts per billion (ppb) for male children and 7.6±1.1 ppb for female children. It can be concluded that off-line fraction of exhaled nitric oxide measurements with dynamic flow restriction are feasible in young children and correspond to on-line values. M.W.H. Pijnenburg was supported by a grant from the Dutch Asthma Foundation and L. Ghiro was supported by a grant of the Italian Nitric Oxide Club (INOC).