TY - JOUR T1 -针灸治疗哮喘的疗效:JF - European Respiratory Journal JO - Eur Respir J SP - 846 LP - 852 DO - 10.1183/09031936.02.00078702 VL - 20 IS - 4 AU - Martin, J. AU - Donaldson, A.N.A. AU - Villarroel, R. AU - Parmar, M.K.B. AU - Ernst, E. AU - Higginson，i.j Y1 - 2002/10/01 UR - //www.qdcxjkg.com/content/20/4/846.abstract N2 -针灸治疗哮喘的随机对照试验的相互矛盾的结果表明，既有有益的影响，也有有害的影响。作者对已发表的文献中所有随机临床试验进行了正式的系统回顾和荟萃分析，这些试验比较了哮喘患者在真实穴位和安慰剂穴位的针灸。作者搜索了1970年至2000年期间发表的试验。试验必须测量以下客观结果中的至少一项:峰值呼气流量、一秒钟用力呼气量(FEV1)和用力肺活量。对针灸和安慰剂之间的标准化平均差异进行了估计，并将其与每次试验相结合，以估计总体效果。根据个别研究的特点，研究异质性。12项试验符合纳入标准，但其中一项试验的数据无法获得。只有3个病例的个人数据可用。 Standardised differences between means ranging from 0.071 to 0.133, in favour of acupuncture, were obtained. The overall effect was not conventionally significant and it corresponds to an approximate difference in FEV1 means of 1.7. After exploring hetereogenenity, it was found that studies where bronchoconstriction was induced during the experiment showed a conventionally significant effect. This meta-analysis did not find evidence of an effect of acupuncture in reducing asthma. However, the meta-analysis was limited by shortcomings of the individual trials, in terms of sample size, missing information, adjustment of baseline characteristics and a possible bias against acupuncture introduced by the use of placebo points that may not be completely inactive. There was a suggestion of preferential publication of trials in favour of acupuncture. There is an obvious need to conduct a full-scale randomised clinical trial addressing these limitations and the prognostic value of the aetiology of the disease. ER -