RT Journal第SR电子T1在哮喘症状患者中增加了肺泡一氧化氮浓度JF欧洲呼吸杂志Jo EUR Respir J FD欧洲呼吸会SP 841 OP 845 Do 10.1183 / 09031936.02.00202002 VO 20是4 A1Lehtimäki,L.A1Kankaanranta188bet官网地址,H. A1 Saarelainen,S. A1 Turjanmaa,V.A1 Moilanen,E. YR 2002 UL //www.qdcxjkg.com/content/20/4/841.Abstract/20/4/841.Abstract Ab夜间哮喘症状和肺功能受损的肺功能与外周肺隔室中的炎症活性有关。在多次呼气流速下呼出的一氧化氮(NO)测量可用于单独评估肺泡和支气管不产生和炎症。作者假设患有夜间症状的哮喘患者患者较高的肺泡没有浓度,而不是只有白天症状。作者询问了40名患者通过使用书面调查问卷对新诊断的类毒素 - 幼稚哮喘患者进行夜间哮喘症状。在40个哮喘和40个健康对照中评估肺泡不浓度和支气管无通量。40名患者的十九名报告夜行症状。夜间症状的患者具有比没有夜间症状的患者(0.8±0.3 ppb,p = 0.012)或健康对照(1.0±0.1ppb,1.7±0.3(平均±0.3(平均±0.3)零件(PPB))的患者(1.7±0.3))(1.0±0.1ppb,p = 0.032)。支气管在患者中,(2.4±0.4nl·s-1,p <0.001),无需(2.6±0.4nl·s-1,p <0.001)夜间症状,与对照相比(0.7±0.1 nL·S-1)。 Nocturnal symptoms in asthmatic patients are related to a higher alveolar nitric oxide concentration. The results suggest that assessment of alveolar nitric oxide concentration can be used to detect the parenchymal inflammation in asthmatic patients with nocturnal symptoms. The study was supported by grants from the National Technology Agency (Tekes), the Medical Research Fund of Tampere University Hospital, Tampere Tuberculosis Foundation, Jalmari and Rauha Ahokas Foundation, and the Academy of Finland.