@article {T {\”= {} rnvik361,作者。T {\”} rnvik和l·巴瑞}标题={]土拉菌病},体积={21}={2},页面= {361 - 373}= {2003},doi ={10.1183 / 09031936.03.00088903},出版商={欧洲呼吸学会},文摘={]土拉菌病是一种人畜共患细菌性疾病的北半球。188bet官网地址土拉杆菌内的病原体,通过直接接触被感染的啮齿动物传染给人类或兔形目动物,产气的曝光,摄入受污染的食物或水,或通过节肢动物叮咬。]土拉菌病的流行程度显示了一个广泛的地理变异。在一些流行地区,爆发频繁发生,而附近的农村地区的国家可能是完全免费的。f .土拉杆菌内兼性胞内病原体及其主要哺乳动物靶细胞是单核吞噬细胞。获得通过皮肤]土拉菌病时,主溃疡往往是发现和总的来说,区域淋巴结变得显著扩大。当吸入萎缩了,疾病可能会出现肺炎。那么频繁,然而,发烧和一般疾病的发展没有呼吸道症状和肺影像学的改变。当礼物,变化差别很大,有时可能会包括门的扩大和淋巴瘤。 Within an outbreak, the first case of tularaemia is not always readily diagnosed. A decade may have lapsed since the disease was encountered and its existence may be more or less forgotten. The difficulty refers especially to the respiratory form, in which symptoms are less specific. In cases of atypical pneumonia or acute febrile disease with no local symptoms, a history of exposure to hares or rodents or merely living in an endemic region should be sufficient to include tularaemia among differential diagnoses. The microbiological diagnosis of tularaemia relies mainly on serology, and the treatment on broad-spectrum antibiotics. For decades, a live vaccine has been successfully used in risk groups but is presently not available due to difficulties in standardisation. This work was supported by grants from the Swedish Medical Research Council, V{\"a}sterbottens l{\"a}ns landsting, and the Medical Faculty, Ume{\r a} University.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/21/2/361}, eprint = {//www.qdcxjkg.com/content/21/2/361.full.pdf}, journal = {European Respiratory Journal} }