RT杂志文章SR电子T1对囊性纤维化婴儿潮汐呼吸参数的评估JF欧洲呼吸杂志JO Eur Respir J FD欧洲呼吸学会SP 761 OP 766 DO 10.1183/09031936.03.00024703 VO 22 IS 5 A1 Ranganathan, S.C. A1 Goetz, I. A1 Hoo, 188bet官网地址A-F。A1 Lum, S. A1 Castle, R. A1 Stocks, J. A1, YR 2003 UL //www.qdcxjkg.com/content/22/5/761.abstract AB需要简单的方法来评估囊性纤维化(CF)婴儿的肺功能。这项研究确定了从潮汐呼吸中获得的简单测量与从更复杂的用力呼气动作中获得的测量之间的关系。健康婴儿和患有CF的婴儿分别来自两家产科单位和五家CF专科医院。测定镇静婴儿的呼吸频率、潮气量、分钟通气和潮气量比(TPTEF:TE)，并与提高容积法测定的0.4秒用力呼气量(FEV0.4)进行比较。总共招募了95名健康婴儿和47名年龄、性别、种族和母亲吸烟比例相似的CF婴儿。健康婴儿和患有CF的婴儿的TPTEF:TE和潮气量没有差异。由于平均呼吸频率增加5.8 (3.2-8.4)min−1(95%置信区间)，患有CF的婴儿的分钟通气显著增加。13例(28%)CF患儿>2 sd时呼吸频率升高。然而，呼吸频率与FEV0.4之间没有关联。潮汐呼吸比在鉴别囊性纤维化婴儿气道功能减弱时无效。 An elevated respiratory rate may be due in part to ventilation heterogeneity but is poorly predictive of diminished airway function measured by forced expiration. This work was supported by the Cystic Fibrosis Trust, the Foundation for the Study of Sudden Infant Death, the Dunhill Medical Trust and Portex Ltd. Research at the Institute of Child Health benefits from research and development funding received from the National Health Service executives.