TY - T1的卧姿在急性呼吸窘迫综合征JF -欧洲呼吸杂志》乔欧元和J SP - 1017 LP - 1028 - 10.1183 / 09031936.02.00401702六世- 20 - 4 AU -佩洛西,p . AU - Brazzi l . AU - Gattinonil . Y1 - 2002/10/01 UR - //www.qdcxjkg.com/content/20/4/1017.abstract N2 -在过去的几年里容易定位已经越来越多地用于治疗急性呼吸窘迫综合征(ARDS)患者,这种策略现在被认为是一个简单而安全的方法,改善氧合。然而，引起呼吸功能改善的生理机制以及真正的临床效益尚不完全清楚。这篇综述的目的是讨论俯卧位在ARDS患者中的生理和临床效果。俯卧位的主要生理目的是:1)改善氧合;2)改善呼吸力学;3)均匀化胸膜压力梯度、肺泡膨胀和通气分布;4)增加肺容积，减少肺不张区数量;5)便于分泌物的排泄;6)减少呼吸机相关肺损伤。 According to the available data, the authors conclude that: 1) oxygenation improves in ∼70–80% of patients with early acute respiratory distress syndrome; 2) the beneficial effects of oxygenation reduce after 1 week of mechanical ventilation; 3) the aetiology of acute respiratory distress syndrome may markedly affect the response to prone positioning; 4) extreme care is necessary when the manoeuvre is performed; 5) pressure sores are frequent and related to the number of pronations; 6) the supports used to prone and during positioning are different and nonstandardised among centres; and 7) intensive care unit and hospital stay and mortality still remain high despite prone positioning. ER -