@Article {Solin717,作者= {Solin,P。和Jackson,D.M。和Roebuck,T。和Naughton,M.T。},Title = {Central Sleep apnea中的心脏舒张功能和高型通气反应},音量= {20},number = {3},Pages = {717---723},Year = Year ={2002},doi = {10.1183/09031936.02.00742002},Publisher = {欧洲188bet官网地址呼吸社会},摘要= {过度换气是有助于发育的关键因素普通的。据报道,ICSA发生在20 \%的左心室舒张功能障碍患者中,其中肺部血管压力升高,导致肺迷走神经传入的增加可能会导致过度换气。测量了对以下ICSA中观察到的过度换气的两种潜在机制的贡献:1)左心室舒张功能障碍诱导的肺动脉高压;和2)增加周围和中央高含量通气反应(HCVR)。在16名患有ICSA的受试者中,测量了在清醒期间测量肺动脉压,左心室舒张功能和对高碳水化合物的化学敏感性。所有受试者均具有收缩的肺动脉压力\ <3.99 kPa(\ <30 mmHg),只有四个患有舒张功能障碍。与历史正常对照受试者相比,所有受试者的外围和中央HCVR均具有升高。 Diastolic dysfunction correlated with increasing age but not with HCVR or markers of central sleep apnoea severity. Idiopathic nonhypercapnic central sleep apnoea is likely to be dependent upon raised hypercapnic ventilatory responses, and not pulmonary hypertension due to left ventricular diastolic dysfunction. P. Solin is a recipient of a National Health and Medical Research Council scholarship.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/20/3/717}, eprint = {//www.qdcxjkg.com/content/20/3/717.full.pdf}, journal = {European Respiratory Journal} }