期刊论文%A Lundberg, j.o.n n %A Palm, j %A Alvingk . % T一氧化氮但不是一氧化碳不断释放人类鼻气道% D 2002% R 10.1183 / 09031936.02.00293702 % % P J欧洲呼吸杂志》100 - 103 V % 20% 1% N X从不同的实验室结果表明一氧化氮(NO)和一氧化碳(CO)在人类共存航空公司在健康和疾病。这些气体存在于人类呼出的气体中,据报道,鼻腔气道中有高浓度的NO和CO。此外,气道炎症患者呼出的CO和NO增加。采用化学发光(NO)和红外(CO)技术在不同的固定流量下同时测量了18名健康受试者口腔呼出的空气和从鼻子取样的空气中的NO和CO。还研究了吸烟对气道NO和CO释放的急性影响。所有受试者均检测到鼻腔NO,其浓度高度依赖于流量(平均±sem: 236±23和527±49 ppb),浓度分别为2和0.5 L·min−1)。相比之下,没有证据表明,无论样品流速如何,CO在鼻腔气道中释放。事实上,额外的实验表明,当低水平的一氧化碳气体通过鼻腔时,会被净吸收。在吸烟后,鼻腔一氧化碳也无法检测到。 Both NO (22±2 ppb) and CO (1.1±0.1 parts per million) were consistently found in orally exhaled air. CO, but not NO, levels increased acutely after smoking a cigarette. The authors conclude that the patterns of nitric oxide and carbon monoxide release in the airways seem to differ profoundly in healthy subjects. Orally exhaled air contains both nitric oxide and carbon dioxide whereas nasal air contains nitric oxide only. This study was supported by grants from The Swedish Research Council, The Heart & Lung Foundation, The Karolinska Institutet and Ruth & Richard Juhlins Foundation. %U //www.qdcxjkg.com/content/erj/20/1/100.full.pdf