@Article {Gaede267，作者= {Gaede，K.i。以及Wilke，G。和Brade，L。和Brade，H。和Schlaak，M。和M {\“ U} ller-Quernheim，J.}，title = {抗chlamydophila Immunoglobulain in carlyagoid and sumydophila Immunoglobulin Perrcience in Carcoidosis and Suptar and as ost statial stitatial pneumoniae}，音量= {19}，number = {2}，pages = {267--274}，年= {2002}，doi = {10.1183/09031936.02.001222002}，publisher = {欧洲呼吸症188bet官网地址和通常的间质性肺炎（UIP）是影响下呼吸道的未知病因的疾病。尽管有许多研究调查了这些疾病的因果作用，但没有微生物可以将其鉴定为因果剂。pneumoniae infections associated with lung injury encouraged the present investigations to screen patients with sarcoidosis and with UIP for their Chlamydophila-specific immune response. Thirty-nine patients with sarcoidosis, 26 patients with UIP and 34 controls were tested for the prevalence of Chlamydophila-specific antibodies在布朗克Hoalveolor灌洗液（BALF）和血清。在针对衣原体脂肪糖（LPS）的属特异性测试中，测试了样品的存在，并在针对肺炎梭状芽胞杆菌的物种特异性测试中进行了测试。这项研究表明，与对照组（8.8 \％）和UIP患者（12.0 \％）相比，在结节病患者BALF（36.8％）中，衣原体dophila LPS特异性免疫球蛋白（Ig）的患病率明显更高。在血清中观察到了类似的发现。在IgG和IgA的结节症患者中，BALF中肺炎特异性抗体的患病率明显更高（IgG：74.4 \％\％\％； IgA：46.2 \％），IgG的UIP（IgG：50.0 \％\％; iga; iga; iga; iga; iga; iga; iga; iga; iga; iga; iga; iga; iga; iga; iga; iga; iga; iga; iga; iga; iga; iga; iga》; igG;％）与对照组（IgG：14.7 \％; IgA：14.7 \％）相比。 The elevated prevalence of Chlamydophila-specific antibodies in sarcoidosis patients might implicate Chlamydophila as a causal agent. However, considering the high prevalence of Chlamydophila antibodies in the healthy population, the data presented might reflect Chlamydophila co-infections in pre-injured lungs seen in these patients.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/19/2/267}, eprint = {//www.qdcxjkg.com/content/19/2/267.full.pdf}, journal = {European Respiratory Journal} }