RT期刊文章SR电子T1标准高压氧处理方案对肺功能的影响JF欧洲呼吸杂志JO EUR RESSIR J FD欧洲呼吸学会SP 1442 OP 1445 VO 12 IS 6 A1 Thorsen,E A1 Ananderud,e A1 Ananderud,L a1 aasen,l a1 aasen,tb yr yr yr188bet官网地址1998 ul //www.qdcxjkg.com/content/12/6/1442.Abstract ab Abs aff a处方与潜水无关的疾病的高压氧(HBO)治疗正在增加。肺氧毒性是众所周知的,但是尚未量化与标准HBO治疗方案相对应的累积氧气暴露的作用。20例患者(10名男性)每天在240 kPa的部分压力下进行21 HBO治疗,持续90分钟。在研究开始时,没有一个以前的肺部疾病,所有肺部射线照相正常和肺功能正常。在治疗期间的第7、14和21天,在治疗后的第7、14和21天,在治疗后的第7、14和21天,在HBO治疗前,在治疗后3-4周测量了动态肺部体积,强迫呼气流量和肺肺的转移因子(TL,CO)。在治疗的最后一周,四名患者(一名男性)报告了非生产性咳嗽。一秒钟(FEV1)(p <0.001),平均强制性呼气流量(FEF25-75%)(p <0.001)(p <0.001)和强迫呼气流量为50和75%的强制性流量,强迫呼气量逐渐减少(p <0.001)(p <0.001)(p <0.001)(p <0.001)HBO治疗期间的生命力(FVC)过期。第21天FEV1的减少为4.4 +/- 1.7%,FEF25-75%10.3 +/- 6.1%。 Four weeks after treatment there was a partial normalization. There were no changes in FVC or peak expiratory flow (PEF). TL,CO was slightly reduced on day 21 of treatment only (p<0.01) and fully normalized 1 month later. A reduction in small airways conductance is consistent with other studies where total oxygen exposures have been below the limit causing toxic pulmonary effects traditionally measured as a reduction in vital capacity. This effect is not considered to be of any clinical significance for patients treated with hyperbaric oxygen unless repeated treatment series are to be given.