TY - JOUR T1 - AutoSet鼻CPAP滴定法:JF -欧洲呼吸杂志JO - Eur Respir J SP - 2073 LP - 2078 DO - 10.1183/09031936.97.10092073 VL - 10 IS - 9 AU - Teschler, H AU - Farhat, AA AU - Exner, V AU - Konietzko, N AU - Berthon-Jones，M Y1 - 1997/09/01 UR - //www.qdcxjkg.com/content/10/9/2073.abstract N2 -我们之前已经证明AutoSet令人满意地改善了阻塞性睡眠呼吸暂停(OSA综合征)受试者的睡眠呼吸障碍和睡眠结构。本研究的目的是确定在AutoSet推荐压力下长期常规定压持续气道正压(CPAP)治疗的受试者是否:长期依从性令人满意;一旦最初的反弹结束，这种改善就会持续下去;滴定压力随时间变化稳定;使用相似的终点，滴定压力与手动滴定压力相当。20名患有阻塞性睡眠呼吸暂停(OSA)的男性患者，之前在诊断夜、手动滴定法和AutoSet滴定法以及AutoSet推荐的固定压力下进行了全面多导睡眠描记术研究，在平均3个月和8个月后，以推荐的固定压力进行了重新研究。重新研究包括家庭呼吸监测(Nellcor EdenTrace)，重复手动和AutoSet滴定与多导睡眠描记仪。通过小时计读数来评估依从性。 Mean (+/-SEM) usage was 5.7 +/- 0.1 h.night-1 at 3 and 8 months. The arousal index remained normalized. Diagnostic respiratory disturbance index (RDI) was 60.3 +/- 5.7 events.h-1. On AutoSet at fixed CPAP, RDI was initially 2.6 +/- 0.7 events.h-1, then rose slightly (p < 0.001) to 4.3 +/- 0.6 events.h-1 at 3 months, and was 3.6 +/- 0.5 events.h-1 at 8 months. AutoSet titration pressure was: 9.9 +/- 0.4 cmH2O initially, 10.6 +/- 0.4 cmH2O at 3 months, and 9.7 +/- 0.5 cmH2O at 8 months (NS). Manual titration pressure at 8 months was 10.4 +/- 0.4 cmH2O. The standard deviation of the discrepancy with AutoSet was 0.84 cmH2O. In conclusion, the AutoSet recommended pressure varies little with time, and closely predicts the final manual titration pressure; the improvement in respiratory disturbance index was largely maintained, and compliance was good, although probably enhanced by close supervision. ER -