%0期刊文章%a romero,s%a hernandez,l%a gil,j%a aranda,i%a martin,c%a sanchez-paya,j%t在纺织品印刷工人中组织肺炎:临床描述%d1998%j欧洲呼吸道杂志%p 265-271%v 11%n 2%X在1992年4月,在西班牙瓦伦西亚自治社区Alcoi地区的充气纺织工人中发生了严重的呼吸疾病。一项流行病学研究将这种爆发与使用重新燃烧的产品Acramin-FWN联系起来。我们分析了前14名确认组织肺炎(OP)的临床,实验室和病理数据,继此后是这种新公认的职业有毒物质。患者的平均年龄为30岁。最常见的临床发现是咳嗽(86%),epistaxis(71%),呼吸困难(64%),压迫性胸痛(57%)和裂纹(50%)。限制性功能模式在64%中显而易见。影像学发现主要由65%的斑点浸润和35%的微型模式组成。用皮质类固醇治疗的14例患者中有11例并不能阻止五名患者的不可逆呼吸衰竭发展。在尸检时,除了OP的特征外,间质性纤维化和弥漫性肺泡损伤还明显。 A low total lung capacity, the presence of crackles at admission, and increases in the alveolar-arterial oxygen difference were predictive of death. The organizing pneumonia caused by the inhalation of Acramin-FWN is characterized by a tendency to evolve into progressive interstitial fibrosis despite the use of corticosteroids. The illness is restricted to the respiratory system and once respiratory failure has developed the prognosis is poor. %U //www.qdcxjkg.com/content/erj/11/2/265.full.pdf