ty -jour t1-在纺织品印刷工人中组织肺炎:临床描述JF-欧洲呼吸杂志JO -EUR RESSIR J SP -265 LP -271 VL -11 VL -11 IS -2 AU -ROMERO -ROMERO -ROMERO,SAU -SAU -HERNANDEZ,L au -GIL -GIL -GIL -GIL -GIL -GIL -GIL -GIL -GIL,j au -aranda,i au -martin,c au -sanchez -paya,j y1-1998/02/01 ur -http://www.qdcxjkg.com/content.com/content/11/1/2/265.abstract N2-1992年4月,在西班牙瓦伦西亚自治社区的Alcoi地区的充气纺织工人中发生了严重的呼吸疾病。一项流行病学研究将这种爆发与使用重新燃烧的产品Acramin-FWN联系起来。我们分析了前14名确认组织肺炎(OP)的临床,实验室和病理数据,继此后是这种新公认的职业有毒物质。患者的平均年龄为30岁。最常见的临床发现是咳嗽(86%),epistaxis(71%),呼吸困难(64%),压迫性胸痛(57%)和裂纹(50%)。限制性功能模式在64%中显而易见。影像学发现主要由65%的斑点浸润和35%的微型模式组成。用皮质类固醇治疗的14例患者中有11例并不能阻止五名患者的不可逆呼吸衰竭发展。在尸检时,除了OP的特征外,间质性纤维化和弥漫性肺泡损伤还明显。 A low total lung capacity, the presence of crackles at admission, and increases in the alveolar-arterial oxygen difference were predictive of death. The organizing pneumonia caused by the inhalation of Acramin-FWN is characterized by a tendency to evolve into progressive interstitial fibrosis despite the use of corticosteroids. The illness is restricted to the respiratory system and once respiratory failure has developed the prognosis is poor. ER -