@article {schonhofer184，作者= {Schonhofer，B和Sonneborn，M和Haidl，P和Bohrer，H和Kohler，d}，title = {比较两种不同的持续性呼吸衰竭模式的慢性呼吸衰竭模式device}，音量= {10}，number = {1}，pages = {184--191}，年= {1997}，publisher = {欧洲呼吸社会}，摘要= {{188bet官网地址最常用的无侵袭性机械通气模式（NMV）是体积控制的间歇性正压通气（IPPV）。压力支持通风最近变得越来越流行，但其优点尚未得到明确定义。在一项开放的非随机随访研究中，我们在6个月内评估了两种模式的NMV模式，体积控制（IPPV）和压力控制通风（PCV）（PCV），连续30例（24名男性和6名女性，年龄为49 +//- 49 +/-19岁）患有慢性呼吸衰竭（CRF）。基线评估包括生理和主观数据。在所有情况下，鼻腔IPPV最初均施用1个月，然后是鼻腔PCV的第二个月。此后，根据患者{\ textquoteright}的主观症状评分和/或超碳酸血症的复发来定义对PCV的反应者或无反应者。在IPPV阶段，除两名患者外，主观和客观参数都显着改善。 During the following 1 month PCV phase, stabilization was maintained in 18 patients ("responders"), while 10 patients were defined as "nonresponders". In nonresponders, hypercapnia increased (arterial carbon dioxide tension (Pa,CO2): 5.7 +/- 0.4 to 6.6 +/- 0.5 kPa; p \< 0.05) and symptom scores decreased. Compared with responders, nonresponders had a lower mean nocturnal arterial oxygen saturation (Sa,O2) (p \< 0.05) and a higher daytime Pa,CO2 (p \< 0.05) at baseline. We con clude that the majority of patients suffering from chronic respiratory failure who are initially satisfactorily ventilated with intermittent positive pressure ventilation may also be adequately maintained with pressure-controlled ventilation. However, there is a subgroup with more severe chronic respiratory failure at baseline, in whom pressure-controlled ventilation is inadequate. After 4 weeks of treatment with pressure-controlled ventilation, the subjective scores and the arterial carbon dioxide tension values reliably distinguished between long-term responders and nonresponders to pressure-controlled ventilation.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/10/1/184}, eprint = {//www.qdcxjkg.com/content/10/1/184.full.pdf}, journal = {European Respiratory Journal} }