ty -jour t1-肺kaposi的肉瘤JF患者的支气管肺泡灌洗液中检测疱疹病毒样DNA - 欧洲呼吸杂志JO -eur Respir J SP -1743 lp -1746 LP -1746 VL -1746 VL -9 IS -8 AU -8 AU -CATHEMAS,GAU -GAU -GAU -GAU -GAU -GAU -GAU -GAU -GAU -GAU -GAU -GAU-Tamm,M au -McGandy,Ce Au -Perruchoud,Ap au -Mihatsch,MJ au -dalquen -dalquen,p y1-1996/08/01 ur -http://www.qdcxjkg.com/content/content/9/8/8/1743/1743/1743/1743.Abtract N2-肺部受累是免疫功能低下患者内脏Kaposi的肉瘤的一种临床重要形式。Recently, herpesvirus-like deoxyribonucleic acid (DNA) sequences, defining a new herpesvirus termed "human herpesvirus 8" (HHV8) or "Kaposi's sarcoma-associated herpesvirus" (KSHV), were detected in Kaposi's sarcoma of acquired immune deficiency syndrome (AIDS)和非辅助患者。我们描述了肺Kaposi肉瘤患者的支气管肺泡(BAL)流体中HHV8 DNA的成功检测。三名免疫功能低下的患者,两名HIV血清阳性,肾移植后1例患有呼吸道症状,并在活检证明了Kaposi的皮肤肉瘤后,在胸部X射线照相后表现出肺部浸润。支气管镜检查显示了典型的Kaposi,就像脱离了内向的损伤一样。使用嵌套聚合酶链反应(PCR)测定法分析BAL流体的HHV8 DNA。在所有三名患者的BAL液中检测到HHV8 DNA。另外,这些患者的皮肤活检组织,淋巴结和外周血单核细胞中可以检测到HHV8 DNA。 Our data show that human herpesvirus 8 deoxyribonucleic acid can be detected in the bronchoalveolar lavage fluid of patients with pulmonary Kaposi's sarcoma. If further studies reveal a high specificity for human herpesvirus 8 deoxyribonucleic acid detection, this test will improve the tools for the diagnosis of pulmonary Kaposi's sarcoma without further need of biopsies. ER -