Ty-Jour T1 - 肺结结抗Borrelia Burgdorferi免疫球蛋白Seroplengence:否则报告JF - 欧洲呼吸期Jo - Eur Respir J SP - 1356 LP - 1358 VL - 10是 - 6 Au - Martens,H Au - Zollner,HAu - Zissel,G Au - Burdon,D Au - Schlaak,M Au - Muller-Quernheim,J Y1 - 1997/06/01 UR - //www.qdcxjkg.com/content/10/6/1356.AbstractN2 - 疾病的疾病仍然不为人知。不能鉴定出一种传染性微生物作为这种疾病的因果剂,但在中国研究中检测到对博尔塞利亚Burgdorferi的高滴度,暗示具有这种疾病的因果关系。然而,这些调查结果不能被其他研究人员复制。因此,这项研究的目的是通过血清学检查评估这些螺旋中这些螺旋可能在结节病发病机制中的作用。检查患有患有顺曲的患者六十六环抗B.Burgdorferi免疫球蛋白通过酶联免疫吸附测定(ELISA)。这些抗体的ELISA显示出高灵敏度,但特异性低;因此,使用特定的免疫印迹来证实阳性结果。 Initially, 8% of the patients were reactive in the ELISA, and 20% of these could be confirmed by immunoblot. Therefore, the prevalence for B. burgdorferi antibodies in sarcoidosis patients was 1.6%. This result did not differ significantly from the prevalence of B. burgdorferi antibodies in 1,000 regular blood donors of the city of Hamburg (7% reactive in the ELISA, 38% confirmed via immunoblot, prevalence 2.7%). The hypothesis of causality between a B. burgdorferi infection and sarcoidosis cannot be confirmed by this data. ER -