TY - JOUR T1 -重度打鼾者和阻塞性睡眠呼吸暂停患者睡眠中的呼气流量限制JF -欧洲呼吸杂志JO - Eur Respir J SP - 2116 LP - 2121 DO - 10.1188 /09031936.96.09102116 VL - 9 IS - 10 AU - Stanescu, D AU - Kostianev, S AU - Sanna, A AU - Liistro, G AU - Veriter，C Y1 - 1996/10/01 UR - //www.qdcxjkg.com/content/9/10/2116.abstract N2 -睡眠时吸气流量限制(FL)先前在阻塞性睡眠呼吸暂停(OSA)患者和重度打鼾者(HS)中均有报道。该实验室的最新研究结果表明，清醒的健康受试者和阻塞性睡眠呼吸暂停患者在肌肉放松时都会出现吸气和呼气流量限制。在这项研究中，我们调查了重度打鼾者和阻塞性睡眠呼吸暂停患者是否在睡眠中出现呼气流量限制。我们研究了4名无呼吸暂停、重度打鼾者和5名OSA患者。用附在紧身衣面罩上的测气仪测量气流，用置于声门上水平的导管测量声门上压力。通过对睡眠中记录的200次呼吸进行目视检查，对血流限制进行评分。约20%的呼吸周期出现孤立吸气流量限制。在重度打鼾者和阻塞性睡眠呼吸暂停患者中观察到的比例大致相同。孤立呼气流量限制记录较少。 Coupled inspiratory and expiratory flow limitations were more numerous, especially in heavy snorers. We conclude that both in heavy snorers and obstructive sleep apnoea patients, inspiratory flow limitation is associated with expiratory flow limitation. This suggests that upper airway obstruction during sleep is both an inspiratory and expiratory event. ER -