RT Journal Article SR Electronic T1双侧淋巴细胞肺泡炎:共同反应后单方面胸辐照摩根富林明欧洲呼吸杂志乔和J FD欧洲呼吸学会SP 727欧元OP 732签证官13是4 A1马丁C A1罗梅罗,年代A1 Sanchez-Paya, J A1 Massuti, B A1 A188bet官网地址rriero, JM A1埃尔南德斯,L年1999 UL //www.qdcxjkg.com/content/13/4/727.abstract AB本研究的主要目的是评估支气管肺泡灌洗(BAL)的早期诊断价值在辐射诱导肺损伤患者乳房癌。26名接受乳腺癌术后放疗的女性在放疗前和放疗后0、15、30、60和180天进行评估。病史、体格检查、胸片和肺功能检查。包括淋巴细胞亚群分析在内的BAL仅限于放疗后的第二次评估。以21例健康女性为对照组。将无症状患者放射治疗后的结果与一组放射性肺炎患者的结果进行比较。放疗组BAL淋巴细胞比例(29.5+/-15.7%)明显高于对照组(6.2+/-3.3%)(p<0.01)。胸部照射侧与未照射侧的BAL检查结果无统计学差异。并发肺炎患者(24.5+/-13.5%)与未并发肺炎患者(32.8+/-16.5%)的BAL淋巴细胞百分比差异无统计学意义。 Patients with pneumonitis at the time of BAL had significantly higher (p<0.05) alveolar CD4 subset cells (24.8+/-10.2%) than asymptomatic patients (15.2+/-8.9%). Maximal reductions in total lung capacity (p<0.01), and residual volume (p<0.05) occurred 60 days after irradiation. The early lymphocytic alveolitis induced by unilateral thoracic radiotherapy in most patients with breast cancer is always bilateral and does not predict the subsequent development of radiological evidence of pneumonitis.