TY -的T1 - 5年随访的肺功能在化学工作者利用瓦斯涌出和阻抗测量JF -欧洲呼吸杂志》乔欧元和J SP - 2109 LP - 2115 - 10.1183 / 09031936.96.09102109六世- 9 - 10盟Keman年代AU -核,B非盟-韦塞尔,GJ盟——Kusters E盟还是婚后,PJ Y1 - 1996/10/01 UR - //www.qdcxjkg.com/content/9/10/2109.abstract N2 -呼吸系统的阻抗测量使用强迫振荡技术(FOT),被多次提议作为职业健康检查的工具。本研究的目的是比较阻抗测量和流量-体积曲线的结果，并研究肺功能下降与特定暴露和吸烟之间的关系。在5年的随访期间(1990-1995年)，这两种测量方法都应用于来自7个主要生产/人员组的136名化学工人。气道阻塞的发生率(1秒用力呼气量(FEV1)和lt;预测的80%)，在两个时间点约为5%，但不一定包括相同的受试者。5年间FEV1平均下降200 mL(预测下降160 mL)。尽管大多数阻抗参数在这两年都与流量体积参数相关，但FEV1 (>330 mL)仅伴随8hz时电抗(X8)的显著降低和共振频率(f0)的增加。有趣的是，FEV1的下降显著依赖于1990年开始时的年龄、工作年限、包龄、FEV1和所有阻抗参数(r = 0.35; p = 0.01). Similarly, the increase in f0 was significantly dependent on age, years of employment, pack-years, f0, FEV1, forced vital capacity (FVC), peak expiratory flow (PEF) and maximal mid-expiratory flow (MMEF) at the start (r = 0.56; p < 0.01). Those with a rapid decline in FEV1, were relatively more represented among acid workers (relative risk (RR) = 2.14), maintenance workers (RR = 2.1) and bulk/transport workers (RR = 1.78), but none of these was significant. Lung function, however, was significantly lower in the bulk/transport workers (n = 14) compared to the rest, based both on flow-volume (FEV1, FVC) and impedance (X8, f0) measurements. Smoking had a significant effect on most flow-volume parameters but only for frequency dependence among the impedance outcomes. It is concluded that alterations in impedance parameters do reflect changes in flow-volume curves induced by age. smoking and occupational exposure. Therefore, these data are a valuable extension to current cross-sectional data. ER -