复合菌群泰的T1 -非结核分枝杆菌pulmonary disease incidence among elderly patients with bronchiectasis JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.00018-2022 VL - 59 IS - 6 SP - 2200018 AU - Kimberly Schildknecht AU - Kevin L. Winthrop AU - D. Rebecca Prevots AU - Rebekah Blakney AU - Emily Henkle Y1 - 2022/06/01 UR - //www.qdcxjkg.com/content/59/6/2200018.abstract N2 - Nontuberculous mycobacteria (NTM) are environmental pathogens causing disease in humans; however, not everyone exposed develops disease [1]. Those with underlying pulmonary diseases, persons over 60 years old and women have an increased risk for nontuberculous mycobacterial pulmonary disease (NTM-PD) [1, 2]. Bronchiectasis is a lung condition characterised by chronic airway dilation and inflammation, resulting in impaired mucus clearance, and is associated with NTM-PD [1–3]. Both NTM-PD and bronchiectasis are increasing in incidence in the USA [2, 3]. Although patients with bronchiectasis are at increased risk of acquiring NTM-PD [1, 2], the incidence of NTM-PD in these patients is not well described. Previous US Medicare data estimated those with bronchiectasis were 50- to 75-fold more likely to have a diagnosis of NTM-PD than those without bronchiectasis [4]. The objective of this analysis was to estimate the incidence of NTM-PD among US Medicare enrolees newly diagnosed with bronchiectasis over the age of 65 years.Incidence of NTM-PD was estimated among US Medicare beneficiaries newly diagnosed with bronchiectasis between 2006 and 2014. Overall incidence of NTM-PD was found to be as high as 1950 per 100 000 person-years. https://bit.ly/3iAr4o5We thank Kevin Ng (OHSU) for technical support generating the datasets for analysis. ER -