TY - JOUR T1: 2017-2019年法国因呼吸道合胞病毒感染住院的成人住院和中期出院后并发症:一项观察性研究摩根富林明-欧洲呼吸杂志》乔和J - 10.1183/13993003.00651 -2021欧元六世- 59 - 3 SP - 2100651 AU Descamps Alexandre AU -兰兹,Nezha盟——Galtier佛罗伦萨AU -莱恩,Fabrice盟——Lesieur代森锌盟——Vanhems菲利普盟——奸情,Selilah AU - L肯,创作的非盟- Fidouh Nadhira盟——Foulongne文森特盟——Lagathu吉赛尔盟——所得钱款,泽维尔AU -默尔,科琳AU -莉娜,布鲁诺盟——Carrat法布里斯盟——Launay至理名言AU - Loubet,保罗•A2 -Y1 - 2022/03/01 UR - //www.qdcxjkg.com/content/59/3/2100651.abstract N2 -目的本研究的目的是描述因流感样疾病(ILI)住院的成人呼吸道合胞病毒(RSV)感染的临床特征、院内和出院后的结果，并与因流感入院的患者进行比较。方法前瞻性地纳入了连续两个冬季(2017/2018和2018/2019)来自法国五所大学医院的患有ILI的成年人。采用多重反转录PCR法检测鼻咽拭子上RSV和流感病毒。将rsv阳性患者与rsv阴性和流感阳性的住院患者进行比较。泊松回归模型用于估计RSV和流感感染之间与住院和出院后结果相关的调整流行率(aPR)。住院结局包括至少一种并发症的发生、住院时间≥7天、重症监护病房住院、使用机械通气和住院死亡。出院后结局包括30天和90天全因死亡率和90天再入院率。结果共纳入1428例ILI住院患者。检出率为8%(114 / 1428)，检出率为31%(437 / 1428)。RSV住院患者的年龄比流感患者大(平均年龄73.0岁比68.8岁，p=0.015)，慢性呼吸道或心脏疾病的频率更高(分别为52%比39%，p=0.012, 52%比41%，p=0.039)，住院时间更长(中位住院时间为8天比6天，p<0.001)。 Anti-influenza therapies were less prescribed among RSV patients than influenza patients (20% versus 66%, p<0.001). In-hospital composite outcome was poorer in RSV patients (aPR 1.5, 95% CI 1.1–2.1) than in those hospitalised with influenza. No difference was observed for the post-discharge composite outcome (aPR 1.1, 95% CI 0.8–1.6).Conclusion RSV infection results in serious respiratory illness, with worse in-hospital outcomes than influenza and with similar midterm post-discharge outcomes.Respiratory syncytial virus infection in hospitalised adults with influenza-like illness was associated with poor in-hospital and midterm post-discharge outcomes, which may be worse than or similar to those of patients with influenza virus infection https://bit.ly/2VAsMhh ER -