@文章{Descamps2100651，作者= {Descamps, Alexandre和Lenzi, Nezha和Galtier, Florence和Lain}，法布里斯和Lesieur, Zineb和Vanhems, Philippe和Amour, S{\'e}lilah和L{\textquoteright}Honneur, Anne-Sophie和Fidouh, Nadhira和Foulongne, Vincent和Lagathu, Gis{\ 'e} le和Duval, Xavier和Merle, Corinne和Lina, Bruno和Carrat，法布里斯和Launay, Odile和Loubet, Paul}，编辑= {，}，标题={2017年法国因呼吸道合胞病毒感染住院的成人住院和中期出院后并发症{\textendash}2019年:观察性研究}，体积={59}，编号={3}，位置-id ={2100651}，年份= {2022}，doi ={10.1181 /13993003.00651-2021}，出版单位={欧洲呼吸学会}，摘要={目的本研究的目的是描述成人流感样疾病(ILI)住院患者呼吸道合胞病毒(RSV)感染188bet官网地址的临床特征和住院及出院后的结局，并与因流感住院的患者进行比较。方法前瞻性地纳入连续两个冬季(2017/2018和2018/2019)在法国五所大学医院住院的患有ILI的成年人。采用多重反转录PCR方法检测鼻咽拭子呼吸道合胞病毒和流感病毒。将rsv阳性患者与rsv阴性和流感阳性住院患者进行比较。泊松回归模型用于估计RSV和流感感染之间与住院和出院后结果相关的调整流行率(aPR)。住院结局由至少一种并发症的发生、住院时间(>=7天)、入住重症监护室、使用机械通气和住院死亡组成。出院后结局包括30和90天全因死亡率和90天再入院率。总的来说，1428名住院的成年ILI患者被纳入研究。RSV阳性率为8\%(1428例中114例)，流感病毒阳性率为31\%(1428例中437例)。呼吸道合胞病毒住院患者比流感患者年龄大(平均年龄73.0岁对68.8岁，p=0.015)，患慢性呼吸道或心脏疾病的频率高(分别为52\%对39\%，p=0.012, 52\%对41\%，p=0.039)，住院时间长(中位住院日8天对6天，p <0.001)。 Anti-influenza therapies were less prescribed among RSV patients than influenza patients (20\% versus 66\%, p\<0.001). In-hospital composite outcome was poorer in RSV patients (aPR 1.5, 95\% CI 1.1{\textendash}2.1) than in those hospitalised with influenza. No difference was observed for the post-discharge composite outcome (aPR 1.1, 95\% CI 0.8{\textendash}1.6).Conclusion RSV infection results in serious respiratory illness, with worse in-hospital outcomes than influenza and with similar midterm post-discharge outcomes.Respiratory syncytial virus infection in hospitalised adults with influenza-like illness was associated with poor in-hospital and midterm post-discharge outcomes, which may be worse than or similar to those of patients with influenza virus infection https://bit.ly/2VAsMhh}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/59/3/2100651}, eprint = {//www.qdcxjkg.com/content/59/3/2100651.full.pdf}, journal = {European Respiratory Journal} }