Ty-Jour T1 - 根据早期微生物反应预测呼吸机相关的肺炎结果：回顾性观察研究JF - 欧洲呼吸期刊Jo - Eur Respir J Do - 10.1183 / 13993003 - 2100620 Au - Ceccato，Adrian Au -Cristina Au - Ferrier，Miquel Au - Martin-Loeches，Ignacio Au - Barbeta，Enric Au - Gabarrús，Albert Au - Cillóniz，Catia Au - Ranzani，Otavio T. Au - De Pascale，Gennaro Au - Nogas，Stefano Au -Di Giannatale，皮埃卢格·奥地里 - 安东·奥·托雷斯，安东尼·y1 - 2021/01/01 ur - //www.qdcxjkg.com/content/early/2021/08/19/13993003.00620-2021.abstract n2 -呼吸机相关的肺炎是危重病患者的发病率的主要传染性原因;然而，目前的指导方针没有提供后续文化的迹象。我们旨在在诊断呼吸机相关的肺炎后3天评估随访培养和微生物反应的作用，作为短期和长期结果的预测因子。我们进行了回顾性分析从2004年至2017年从上向期收集的群组。基于临床，射线照相和微生物标准诊断呼吸机相关的肺炎。对于微生物鉴定，在72小时后进行气管藻床加吸术并重复。我们在比较两个气管支气管的吸气结果时定义了三组：持续性，超育和消除致病病原体。一百五十七名患者在研究中招生，其中67中存在微生物持久性，超育和根除。72hs后，48％），25％（16％）和65（41％）。具有超育的人在重症监护病房（P = 0.015）和90天（P = 0.036）中具有最高的死亡率，同时也具有最少的空气通风天（P = 0.024）。多变量分析显示VAP诊断时的冲击（差异比率[或] 3.43; 95％置信区间[CI] 1.25至9.40），VAP诊断（或2.87; 95％CI 1.06至7.75）的葡萄球菌分离，以及VAP诊断的低温 (OR 0.67; 95%CI 0.48 to 0.95, per +1°C) to be associated with superinfection.Our retrospective analysis suggests that ventilator-associated pneumonia short-term and long-term outcomes may be associated with superinfection in follow-up cultures. Follow-up cultures may help guiding antibiotic therapy and its duration. Further prospective studies are necessary to verify our findings.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Ceccato has nothing to disclose.Conflict of interest: Dr. Dominedo has nothing to disclose.Conflict of interest: Dr. Ferrer has nothing to disclose.Conflict of interest: Dr. Martin-Loeches has nothing to disclose.Conflict of interest: Dr. Barbeta has nothing to disclose.Conflict of interest: Mr. Gabarrús has nothing to disclose.Conflict of interest: Dr. Cilloniz has nothing to disclose.Conflict of interest: Dr. Ranzani has nothing to disclose.Conflict of interest: Dr. De Pascale has nothing to disclose.Conflict of interest: Dr. Nogas has nothing to disclose.Conflict of interest: Dr. Di Giannatale has nothing to disclose.Conflict of interest: Dr. Antonelli has nothing to disclose.Conflict of interest: Dr. Torres has nothing to disclose. ER -