TY -的T1 - < em >绿脓杆菌< / em >时代dication after lung transplantation: is it the tip of the iceberg? JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.04380-2020 VL - 58 IS - 1 SP - 2004380 AU - Messika, Jonathan AU - Bunel, Vincent AU - Weisenburger, Gaelle AU - Godet, Cendrine AU - Mal, Hervé Y1 - 2021/07/01 UR - //www.qdcxjkg.com/content/58/1/2004380.abstract N2 - Chronic lung allograft dysfunction (CLAD) remains the leading cause of death after 1 year post-lung transplantation (LT). As such, every effort to decrease, or to delay, CLAD occurrence must be commended. With this in mind, we read with much interest the study by De Muynck et al. [1]. In this retrospective study of 662 LT recipients in the University Hospitals Leuven, the authors show that CLAD-free survival and graft-survival is significantly better in patients in whom Pseudomonas aeruginosa was never isolated in the respiratory tract. Moreover, in the 95 patients with at least one episode of P. aeruginosa isolation, a significantly better outcome was reported for those whose P. aeruginosa was deemed to be “successfully eradicated” and, on the contrary, significantly lower survival, lower CLAD-free survival and graft survival, and a more pronounced decrease in forced expiratory volume in 1 s during the first year was found when P. aeruginosa eradication was not achieved. These findings are of utmost interest, and the authors, belonging to a very well-known team, with a long-lasting expertise on LT, should be commended for having conducted this study.Is respiratory Pseudomonas aeruginosa infection or persistence in lung transplant recipients an early marker of an emerging chronic lung organ dysfunction? Or its by-product? https://bit.ly/3nyPHlW ER -