%0期刊文章%a peris,marisa%alópez-nuñez,juan J.%a maestre,ana%a jimenez,david a muriel,alfonso%a bikdeli,behnood a weinberg a weinberg,ido%Mazzolai,Lucia%A Lorenzo,Alicia%A Monreal,Manuel%A Riete研究人员%T临床特征和3个月的临床结果相对临床怀疑和确认的肺栓塞%D 2021%R 10.1183/13993003.02723-2020%J欧洲呼吸期刊%p 2002723%v 58%n 1%x背景当前的准则表明,治疗与患有偶然肺栓塞(PE)的癌症患者(PE)类似的治疗癌症患者临床怀疑和确认的PE。然而,这些演示文稿的自然历史尚未得到彻底比较。我们使用了Riete(Informatizado de Enfermedadtromboembólica)注册表的数据,以比较活跃癌症和偶然PE的患者的3个月结果与临床怀疑的患者相比并确认PE。主要结果是90天全因死亡率。次要结局是与PE相关的死亡率,有症状的PE复发和重大出血。从2012年7月到2019年1月,有946例附带无症状PE和2274例癌症患者纳入了临床怀疑和确认的PE。大多数患者(95%对90%)接受低分子量肝素治疗。在最初的90天内,有598例患者死亡,其中包括42例PE。附带PE患者的全因死亡率低于怀疑和确认的PE的患者(11%对22%;或0.43,95%CI 0.34–0.54)。与PE相关的死亡率(0.3%和1.7%; OR 0.18,95%CI 0.06-0.59)的结果是一致的。 Multivariable analysis confirmed that patients with incidental PE were at lower risk of death (adjusted OR 0.43, 95% CI 0.34–0.56). Overall, 29 (0.9%) patients developed symptomatic PE recurrences, and 122 (3.8%) had major bleeding. There were no significant differences in PE recurrences (OR 0.62, 95% CI 0.25–1.54) or major bleeding (OR 0.78, 95% CI 0.51–1.18).Conclusions Cancer patients with incidental PE had a lower mortality rate than those with clinically suspected and confirmed PE. Further studies are required to validate these findings, and to explore optimal management strategies in these patients.In cancer patients with incidental pulmonary embolism the risk of venous thromboembolism recurrences or major bleeding are similar, with a lower mortality https://bit.ly/36AVqSy %U //www.qdcxjkg.com/content/erj/58/1/2002723.full.pdf