TY - T1的临床特点和三个月的结果在癌症患者的< em >和< / em >临床疑似和确诊肺栓塞JF -欧洲呼吸杂志》乔和J - 10.1183/13993003.02723 -2020欧元六世- 58 - 1 SP - 2002723 AU -珀里斯,玛丽莎AU - Lopez-Nunez,胡安·J . AU - MaestreAna AU - Jimenez, David AU - Muriel, Alfonso AU - Bikdeli, Behnood AU - Weinberg, Ido AU - Ay, Cihan AU - Mazzolai, Lucia AU - Lorenzo, Alicia AU - Monreal,目前的指南建议对偶然发生肺栓塞(PE)的癌症患者的治疗与临床怀疑和证实的PE相似。然而,这些陈述的自然史并没有被彻底的比较。方法我们使用来自RIETE (Registro Informatizado de Enfermedad TromboEmbólica)注册的数据,比较活动性癌症和偶发PE患者与临床怀疑和确诊PE患者的3个月预后。主要结果为90天全因死亡率。次要结果是PE相关死亡率、PE症状复发和大出血。结果2012年7月至2019年1月,共纳入946例偶发无症状PE患者和2274例临床怀疑和确诊PE患者。大多数患者(95%对90%)接受了低分子肝素治疗。在前90天,598例患者死亡,其中42例死于PE。 Patients with incidental PE had a lower all-cause mortality rate than those with suspected and confirmed PE (11% versus 22%; OR 0.43, 95% CI 0.34–0.54). Results were consistent for PE-related mortality (0.3% versus 1.7%; OR 0.18, 95% CI 0.06–0.59). Multivariable analysis confirmed that patients with incidental PE were at lower risk of death (adjusted OR 0.43, 95% CI 0.34–0.56). Overall, 29 (0.9%) patients developed symptomatic PE recurrences, and 122 (3.8%) had major bleeding. There were no significant differences in PE recurrences (OR 0.62, 95% CI 0.25–1.54) or major bleeding (OR 0.78, 95% CI 0.51–1.18).Conclusions Cancer patients with incidental PE had a lower mortality rate than those with clinically suspected and confirmed PE. Further studies are required to validate these findings, and to explore optimal management strategies in these patients.In cancer patients with incidental pulmonary embolism the risk of venous thromboembolism recurrences or major bleeding are similar, with a lower mortality https://bit.ly/36AVqSy ER -