% 0期刊文章%查尔默斯,詹姆斯d·%克莱顿,梅根·l . % Goeminne, Pieter c %曹,本%亨伯特,Marc % Shteinberg,安东尼奥由于米甲%,怀中m % Ulrik,夏洛特恋爱补给品%公园,海伦%王,陈% Vandendriessche,托马斯%瞿,杰明% Stolz, Daiana % Brightling,克里斯托弗·% Welte,托拜厄斯Aliberti %,2019冠状病毒病(COVID-19)住院成人患者管理:欧洲188bet官网地址呼吸学会生活指南2021% % D R 10.1183/13993003.00048 J欧洲呼吸杂志-2021% % P 2100048 V % 57% 4% N X冠状病毒疾病患者介绍住院2019 (COVID-19)由于SARS-CoV-2感染有很高的死亡率,经常需要无创呼吸支持或入侵通风。通过循证指南优化和标准化管理可以提高护理质量,从而改善患者的预后。方法由欧洲呼吸学会和中国胸科协会支持的一个工作组使用PICO188bet官网地址(人群、干预、比较者、结果)格式确定了该“生活指南”最初版本的优先干预措施(药理学和非药理学)。GRADE方法用于评估证据的质量和建议的力度。进行了系统的文献综述,并在可能的情况下通过meta分析汇集数据。提出了证据表,并使用决策框架中的证据来制定建议。结果基于现有证据的指南开发(2月20日,2021年),面板会强烈建议支持系统的使用糖皮质激素的患者需要补充氧气或通气支持,并在住院患者使用抗凝。 The panel makes a conditional recommendation for interleukin (IL)-6 receptor antagonist monoclonal antibody treatment and high-flow nasal oxygen or continuous positive airway pressure in patients with hypoxaemic respiratory failure. The panel make strong recommendations against the use of hydroxychloroquine and lopinavir–ritonavir. Conditional recommendations are made against the use of azithromycin, hydroxychloroquine combined with azithromycin, colchicine, and remdesivir, in the latter case specifically in patients requiring invasive mechanical ventilation. No recommendation was made for remdesivir in patients requiring supplemental oxygen. Further recommendations for research are made.Conclusion The evidence base for management of COVID-19 now supports strong recommendations in favour and against specific interventions. These guidelines will be regularly updated as further evidence becomes available.The ERS guidelines for the management of COVID-19 makes recommendations in favour of corticosteroids, thromboprophylaxis, anti-IL-6 and noninvasive ventilatory support. These guidelines will be regularly updated as further evidence becomes available. https://bit.ly/2OlpniF %U //www.qdcxjkg.com/content/erj/57/4/2100048.full.pdf