ty -jour t1-欧洲社区居民老年人的呼吸道合胞病毒感染负担(Resceu):一项国际前瞻性队列研究JF-欧洲呼吸杂志JO -EUR RESSIR J DO -10.1183/139993003.02688-2020-2020202020 VL -574 SP -2002688 AU -KORSTEN,KOOS AU -ADRIAENSSENS,NIELS AU -COENEN,COENEN,SAMUEL AU- BUTLER,CHRISTOPHER AU -RAVANFAR,BEHNAZ AU -RUTTER AU -RUTTER AU -HEATHER AU- HEATHE AU -ALLEN,ALLEN,JULIE AU -JULIE AU -FALSEY,ANN AU -PIRCON,JEAN -PIRCON,JEAN -PIRCON- JEAN -PIRCIRCON,JEAN -JEAN -JEAN -JEAN -JEAN -JEAN -JEAN -JEAN -JEAN -JEAN -JEAN -JEAN -JEAN-Yves AU - Gruselle, Olivier AU - Pavot, Vincent AU - Vernhes, Charlotte AU - Balla-Jhagjhoorsingh, Sunita AU - Öner, Deniz AU - Ispas, Gabriela AU - Aerssens, Jeroen AU - Shinde, Vivek AU - Verheij, Theo AU -Bont,Louis au -Wildenbeest,Joanne A2-,Y1-2021/04/01 Ur -http://www.qdcxjkg.com/content/57/4/4/2002688.Abstract N2 -N2-呼吸道合成病毒(RSV)感染(RSV)感染(RSV)成人被认可,但社区的负担仍然不确定。这项欧洲研究发现,RSV感染很普遍,但在社区居住的老年人中很少引起严重疾病。https://bit.ly/30gsimdbackground呼吸综合病毒(RSV)感染老年人被认为是重要的健康问题。我们旨在评估欧洲的RSV社区负担,年龄≥60岁。方法是欧洲(Resceu)呼吸道合胞病毒联盟的一部分国际,潜在的,前瞻性的观察队列研究。参与者是在两个独立的RSV季节之前通过全科医生(GPS)办事处招募的。参与者每周报告一个RSV季节急性呼吸道感染(ARTI)的症状。 ARTI patients were tested for RSV during home visits and completed a daily symptom diary. RSV illness included PCR-confirmed ARTI and those showing seroconversion over the season. RSV ARTI was based on PCR alone (ClinicalTrials.gov, NCT03621930).Results We recruited 1040 participants (527 in season 2017–2018 and 513 in season 2018–2019) with a median age of 75 years (range 60–100 years). Of these, 1023 (99%) lived independently at home at baseline. RSV illness incidence was 22 out of 527 (4.2%) and 37 out of 513 (7.2%) in the respective seasons. RSV illness did not affect frailty or cardiopulmonary status during the course of the study. No patients were hospitalised or died from RSV illness. In the 36 patients with PCR confirmed RSV ARTI, symptom duration averaged 19 days, while a doctor's visit took place in 11 out of 36 cases (31%). RSV ARTI could not be differentiated clinically from all other ARTIs based on symptoms.Conclusion This European study showed that RSV is prevalent in community-dwelling older adults and rarely causes severe disease. This suggests that watchful waiting, using a continuity of care approach to identify those who do need more intensive care, is often justified when RSV is suspected in family practice. ER -