RT期刊文章SR电子T1肥胖患者新成人哮喘的长期预后JF欧洲呼吸杂志188bet官网地址Adrienn A1 Tuomisto，Leena E. A1Vähätalo，Iida a1niemelä，onni a1 nieminen，pentti a1 kankaanranta，hannu yr yr yr 2021 ul //www.qdcxjkg.com/erjournals.com/content.com/content/content/57/4/4/4/4/4/2001209.absbackter与横断面研究中哮喘的不良结局有关，但肥胖对哮喘的长期影响仍然未知。研究肥胖的影响，在诊断成人哮喘的诊断时发现，对12年的预后进行了研究。专注于口服皮质类固醇（OCS）的使用和呼吸道相关的医院入院。用诊断性体重指数（BMI）（<25 kg·M-2 kg·M-2，25–29.9 kg·M -2，≥30kg·M − 2），然后持续12年作为Seinäjoki成人哮喘研究的一部分。在12年期间评估了自我报告和分配的OC。根据病历分析了医院入院的数据。诊断12年后，有86％的肥胖患者（BMI≥30kg·M -2）在诊断时仍然肥胖。在随访期间，BMI类别之间的体重增加没有差异。在为期12年的随访期间，肥胖的患者报告说，OCS课程的使用量更高（46.9％对23.1％，P = 0.028），更频繁地分配OCS（81.6％对56.9％，P = 0.014），在AT与正常重量患者相比，较高剂量（中位数1350（四分位数280–3180）毫克与600（0-1650）毫克泼尼松龙，P = 0.010）。 Furthermore, patients who were obese had more often one or more respiratory-related hospitalisations compared to normal-weight patients (38.8% versus 16.9%, p=0.033). In multivariate logistic regression analyses, obesity predicted OCS use and hospital admissions.Conclusions In adult-onset asthma, patients obese at diagnosis mostly remained obese at long-term and had more exacerbations and respiratory-related hospital admissions compared to normal-weight patients during 12-year follow-up. Weight loss should be a priority in their treatment to prevent this outcome.Obese patients with new adult-onset asthma often remain obese in the long-term and have more exacerbations and respiratory-related hospital admissions during follow-up. High priority should be given to weight loss during treatment to prevent this outcome. https://bit.ly/2G5HtRZ