在COVID-19 TY - T1的肺栓塞:d dimer threshold selection should not be based on maximising Youden's index JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.04279-2020 VL - 57 IS - 2 SP - 2004279 AU - Korevaar, Daniël A. AU - van Es, Josien Y1 - 2021/02/01 UR - //www.qdcxjkg.com/content/57/2/2004279.abstract N2 - The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has raised new challenges in the diagnosis of pulmonary embolism (PE) [1]. Patients with coronavirus disease 2019 (COVID-19) are at increased risk of developing venous thromboembolism, but symptoms of COVID-19 and PE may overlap, which makes it difficult to identify those with a higher likelihood of PE. Simple and minimally invasive diagnostic algorithms that can safely rule-out PE in patients with COVID-19 are urgently needed. Therefore, we read with interest the recent paper by Mouhat et al. [2] in the European Respiratory Journal.D-dimer thresholds for ruling-out pulmonary embolism should not be selected based on the “optimal” Youden's index https://bit.ly/2Mfp4on ER -