TY - JOUR T1 -慢性肺曲霉病:患病率,有利于肺部疾病和预后JF -欧洲呼吸杂志》乔和J - 10.1183/13993003.03345 -2020欧元SP - 2003345 AU -管家,托马斯•AU - Cottenet乔纳森盟——补钉,Cendrine盟——Roussot阿德里安·非盟- Abdoul Carime, Nafiz盟——好吧,Vichita盟——鹦鹉,安东尼盟——Bonniaud Philippe AU - Quantin慢性肺曲霉病(CPA)是常见慢性肺病(CPD)患者的一种新发疾病。虽然结核病流行与流行国家的结核病有关，但在结核病发病率低的国家缺乏流行病学和预后数据。这项研究的目的是描述2009年至2018年在法国住院的CPA患者的这些特征。我们使用法国全国行政医院数据库估计了CPA住院患者的患病率和死亡率。我们还评估了与cpd、胸部干预和营养不良的关系。2009年至2018年，法国有17 290名CPA患者住院，在此期间患病率不断上升。大多数患者为男性(63.5%)，注册会计师诊断时中位年龄为65岁，居住在农村和大城市。在过去5年中，潜在慢性阻塞性肺病(COPD)和肺气肿的比例分别为44%和22%，而结核和非结核分枝杆菌(NTM)感染的比例仅为3%。 The mortality rates during the first hospitalisation, at 1 year, and at 5 years were 17%, 32%, and 45%, respectively. In multivariate analysis, mortality rates were increased in patients aged over 65 years, males and patients with malnutrition, diabetes, or lung cancer history. The risk of mortality in patients with COPD or emphysema was higher compared to those with previous mycobacterial lung infection.In France CPA is an emerging infection commonly associated with non-mycobacterial CPD. This shift in the distribution profile of underlying CPD will likely worsen CPA mortality.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Maitre has nothing to disclose.Conflict of interest: Dr. Cottenet has nothing to disclose.Conflict of interest: Cendrine Godet: received consultancy or speaker fees, travel support from Pfizer, Astellas, Gilead, MSD, SOS Oxygene, Elivie, Pulmatrix and ISIS Medical.Conflict of interest: Dr. Roussot has nothing to disclose.Conflict of interest: Dr. Abdoul Carime has nothing to disclose.Conflict of interest: Dr. Ok has nothing to disclose.Conflict of interest: Dr. Parrot has nothing to disclose.Conflict of interest: Dr. Bonniaud has nothing to disclose.Conflict of interest: Dr. Quantin has nothing to disclose.Conflict of interest: Dr. Cadranel has nothing to disclose. ER -