RT期刊文章SR电子T1与睡眠相关的呼吸障碍和肺动脉高压188bet官网地址YR 2021 UL //www.qdcxjkg.com/content/57/1/1/2002258.Abstract ABSTRACT AB与睡眠相关的呼吸障碍（SBD）包括阻塞性呼吸暂停，中央呼吸暂停，中央呼吸暂停和与睡眠相关的呼吸症。这些夜间事件有可能在睡眠期间和醒来状态增加肺动脉压（PAP）。“纯”阻塞性睡眠呼吸暂停综合征（OSA）是尚未证明临床影响的PAP的少量增加。相比之下，在肥胖性不足综合征（OHS）或重叠综合征（慢性阻塞性肺疾病（COPD）与阻塞性睡眠呼吸暂停（OSA）（OSA））中，夜间呼吸事件有助于肺动脉高度（PH）的发展，这通常是严重。在后一种情况下，SBD的治疗对于改善肺血流动力学至关重要。患有肺动脉高压（PAH）或慢性血栓栓塞性肺动脉高压（CTEPH）患者有患SBD的风险。在睡眠期间，可以观察到阻塞性和中央呼吸暂停以及通风不匹配的恶化 - 灌注不匹配。在这样的患者人群中，应该强烈怀疑SBD。但是，尚待指定睡眠研究和记录的类型的确切指示。 The diagnosis of OSAS in patients with PAH or CTEPH should encourage treatment with continuous positive airway pressure (CPAP). The presence of isolated nocturnal hypoxaemia should also prompt the initiation of long-term oxygen therapy. These treatments are likely to avoid worsening of PH; however, it is prudent not to treat central apnoea and Cheyne–Stokes respiration (CSR) with adaptive servo-ventilation in patients with chronic right-heart failure because of a potential risk of serious adverse effects from such treatment.In this review we will consider the current knowledge of the consequences of SBDs on pulmonary haemodynamics in patients with and without chronic respiratory disease (group 3 of the clinical classification of PH) and the effect of treatments of respiratory events during sleep on PH. The prevalence and consequences of SBDs in PAH and CTEPH (groups 1 and 4 of the clinical classification of PH, respectively), as well as therapeutic options, will also be discussed.In some clinical situations, important to identify, sleep-related breathing disorders can be responsible for severe pulmonary haemodynamic consequences. In these situations, it is important to treat apnoeas, hypopnoeas and nocturnal oxygen desaturations. https://bit.ly/30akkoM